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Cognitive Bias Modification for Memory Bias (CBM-M) May Help Reduce Stress

Summary

The study provides the first evidence that memory-based training reduces stress and alters its underlying neurobiological mechanisms

Negative memory bias, the tendency to remember negative experiences more easily than positive ones, can fuel cycles of anxiety and depression. In a recent study, researchers from the University of Toyama identified Cognitive bias modification for memory bias (CBM-M) as a potential, accessible intervention for people at risk. Using a randomized controlled trial and brain imaging techniques, the study shows that CBM-M can reduce psychological and biological stress and alter brain circuits linked to emotional memory.

  • Image title: Effects of cognitive bias modification for memory (CBM-M) compared with sham training
  • Image caption: Compared with sham training, CBM-M specifically lowered cortisol levels and stress vulnerability, whose magnitudes were correlated with reduced negative memory bias. Brain scans showed it also strengthened connectivity between the amygdala and the anteromedial orbitofrontal cortex, suggesting a neural mechanism for its benefits.
  • Credit:Professor Yuko Hakamata from the University of Toyama, Japan
  • License type:CC BY-NC-ND 4.0
  • Usage restrictions:Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted.

Research Details

Cognitive Bias Modification for Memory Bias (CBM-M) May Help Reduce Stress[PDF, 297KB]

Reference

Title of original paper

The effectiveness and neurobiological actions of memory bias modification: a randomized controlled trial

Journal

Psychological Medicine

DOI

https://doi.org/10.1017/S0033291725102535

Additional information for EurekAlert

Latest Article Publication Date

24 December 2025

Method of Research

Randomised controlled/clinical trial

Subject of Research

People

Conflicts of Interest Statement

The authors declare none.

Media contact

Yumiko Kato

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